Hughesstovin syndrome hss is a lifethreatening disorder, believed to be a cardiovascular clinical. Antiphospholipid syndrome is an autoimmune disorder in which the immune system attacks phospholipids. Sticky blood systemic antiphospholipid antibody syndrome. Aps support uk for people with antiphospholipid syndrome. Hughes stovin syndrome synonyms, hughes stovin syndrome pronunciation, hughes stovin syndrome translation, english dictionary definition of hughes stovin syndrome. The period was characterized by financial deregulation, the global economic crisis, and bank restructuring programs. Hughes stovin syndrome hss is a lifethreatening disorder, believed to be a cardiovascular clinical variant manifestation of behcets disease bd. Patients affected by this syndrome are often young adult men in the second to fourth decade of life. Hughesstovin syndrome with pulmonary aneurysms and renal. Pulmonary artery aneurysms paa are uncommon, with a diverse differential diagnosis. Antiphospholipid antefosfolipid antibody syndrome aps is an autoimmune disorder.
Hughesstovin syndrome hss is a vasculitis that predominantly affects large vessels. Hughesstovin syndrome orphanet journal of rare diseases. Hughesstovin syndrome synonyms, hughesstovin syndrome pronunciation, hughesstovin syndrome translation, english dictionary definition of hughesstovin syndrome. This study examines the impacts of merger on deposit money banks performance in nigeria between 2000 and 2009. Systemic antiphospholipid antibody syndrome, antiphospholipid. Hsf offers understanding and support to sufferers of hughes syndrome which is known medically as antiphospholipid syndrome aps. In 1983 and during the following two years, the lupus research unit at st thomas published a number of papers showing that certain blood proteins antiphospholipid antibodies were associated with a syndrome of clotting thrombosis, recurrent miscarriages and brain disease. The goals in the management of persistently aplpositive aps patients is. Epidemiology it occurs predominantly between the 2nd to 4th decades. This means people with aps are at greater risk of developing conditions such as.
The disease bears some resemblance to behcet disease. Hughesstovin syndrome, pulmonary artery aneurysms and deep venous thrombosis. Hughesstovin syndrome is a rare condition, characterized by the combination of multiple pulmonary artery aneurysms and peripheral venous thrombosis, that mainly affects males 8090% of cases between the second and fourth decades of life 711. Nonprogressive cerebellar ataxia and previous undetermined acute cerebellar injury. Systemic antiphospholipid syndrome, antiphospholipid syndrome information and help pages for aps patients, doctors and medical professionals antiphospholipid syndrome systemic antiphospholipid syndrome aps is a disorder characterized by recurrent venous or arterial thrombosis andor fetal losses associated with typical laboratory abnormalities. Antiphospholipid syndrome aps, sometimes known as hughes syndrome, is a disorder of the immune system that causes an increased risk of blood clots. Life threatening hemoptysis from hughes stovin syndrome. Clip2, eln, gtf2i, gtf2ird1, and limk1 are among the genes that are typically deleted in people with williams syndrome. Autoimmune disorders occur if the bodys immune system makes antibodies that attack and damage tissues or cells. Sep 21, 2018 williams syndrome is caused by a missing piece deletion of genetic material from a specific region of chromosome 7. Hughes syndrome, also known as antiphospholipid syndrome aps or sticky blood syndrome is an autoimmune condition which affects the blood and its ability to clot.
Understanding elastin and its role in ws a webcast by sarah moonier. I was diagnosed with hughes syndrome after several recurrent miscarriages between 1012 weeks and the only time i have taken medication has been dur. We also decided to combine pulse therapy with methylprednisolone 1 g for three. They first described the findings of the syndrome deep venous thrombosis and segmental pulmonary artery aneurysms in a total of four male patients with pulmonary artery aneurysms in 1959. It is a rare variant of behcets disease, which entails more general problems with the. Hughes stovin syndrome is a rare disorder of unknown etiology characterized by the association of multiple pulmonary artery aneurysms and deep venous thrombosis. Although most are asymptomatic at diagnosis, fatal aneurysm rupture occurs in onethird and dissection in onefifth. Its prime objective is to educate both the medical profession and the general public about a seriously underdiagnosed condition. They described the syn drome in two male patients with deep venous thrombosis and segmental pul.
In the merger syndrome literature, emotions are mentioned, but their role, antecedents and consequences are discussed only at a very general level. Hughes syndrome, also known as antiphospholipid syndrome or sticky blood is a disorder characterized by blood clotting, both in the arteries and veins. Have you suffered from a number of miscarriages but dont know why. Bring patients to the table during hospital merger negotiations, report suggests. The effect of merger on deposit money banks performance in. Hughesstovin syndrome hss is a very rare clinical disorder characterized by thrombophlebitis and multiple pulmonary andor bronchial. While the term merger syndrome enjoys the status of a buzzword, there is little systematic and structured analysis concerning its conceptualization, antecedents and consequences. Hughes syndrome is caused by the presence of antibodies in the blood, called antiphospholipid antibodies. A case of hughesstovin syndrome university of twente research.
Williams syndrome is caused by a missing piece deletion of genetic material from a specific region of chromosome 7. Hughes syndrome a patients guide to the antiphospholipid syndrome dr graham hughes preface. Preoperative assessment patient should be carefully questioned about bleeding, thrombosis and immune disorders. Liberating ministry from the success syndrome is a welcome addition to a number of books written in recent years attempting to combat an unbiblical view of ministry that currently has its foothold in the church at large. Hughes stovin syndrome is a rare condition, characterized by the combination of multiple pulmonary artery aneurysms and peripheral venous thrombosis, that mainly affects males 8090% of cases between the second and fourth decades of life 711. Aps support uk aims to achieve earlier diagnosis and offer support to anyone affected by antiphospholipid syndrome. Less than 40 published cases of hss have been described in english medical literature so far.
A fierce healthcare article on why patients should play a larger role in hospital merger negotiations, citing an nyshealthfunded report by mergerwatch, a patients rights group. Antiphospholipid syndrome aps is a blood clotting disorder that can cause strokes, heart attacks and dvts. Med any combination of signs and symptoms that are indicative of a particular disease or disorder syndrome, mr. The cause of ws williams syndrome is classified as a microdeletion genetic disorder. Antiphospholipid antibody syndrome is present if at least one of these clinical criteria and one of these laboratory criteria are present in patient.
Hughesstovin syndrome article about hughesstovin syndrome. Sep 20, 2002 living with hughes syndrome by triona holden, 9780859698849, available at book depository with free delivery worldwide. Antiphospholipid syndrome fact sheet aps support uk is the only uk registered charity dedicated to raising awareness and funding research into antiphospholipid syndrome aps. Male infertility in young syndrome is secondary to obstructive azoospermia, a condition in which sperm are produced but do not mix with the rest of the ejaculatory fluid, due to a physical obstruction in the epididymis tube through which sperm exit. Hughesstovin syndrome is a rare autoimmune disorder of unknown cause that is characterized by the combination of multiple pulmonary artery aneurysms and. Hughes syndrome is also known as sticky blood syndrome, as its an autoimmune disease where theres an increased tendency for the blood to clot too quickly, both. Hughesstovin syndrome definition of hughesstovin syndrome. Young syndrome genetic and rare diseases information center. Aps is a rare immunological disorder characterized by recurring blood clots. Hughesstovin syndrome is a rare disorder of unknown etiology characterized by the association of multiple pulmonary artery aneurysms and deep venous thrombosis. The etiology is still not known but it is considered to be manifestation of systemic vasculitis.
John patterson hughes and peter george ingle stovin. Hunsaker and coombs 1988, 58 noticed particular expressed of emotional reactions experienced by employees during a merger or acquisition they have named this phenomenon the merger emotions syndrome. Diagnosis of aps is based on the results of specific blood tests and a medical assessment. Our goal is to be the goto resource for autoimmune disease. Hughesstovin syndrome is a rare autoimmune disorder of unknown cause that is characterized by the combination of multiple pulmonary artery aneurysms and deep vein thrombosis.
Hughes stovin syndrome hss is a very rare clinical disorder characterized by thrombophlebitis and multiple pulmonary andor bronchial aneurysms. The first chapter of the first section is disappointed dreams. Are you prone to limb pain and circulation problems. Aps support uk for people with antiphospholipid syndrome, basingstoke. Our daily pick of the best tools and articles to help you care for yourself during lockdown. Aps provokes blood clots in both arteries and veins as well as pregnancyrelated complications such as miscarriage, stillbirth, preterm delivery, and severe preeclampsia. Occasional press stories report misdiagnosis of hughes syndrome as multiple sclerosis, but this seems to be rare. Antiphospholipid syndrome aps, also known as hughes syndrome, is a disorder of the immune system that causes an increased risk of blood clots and miscarriages. Assessment of disease activity by patients with juvenile. Hughesstovin syndrome hss is an extremely rare condition characterised by pulmonary artery aneurysms and deep vein thrombosis dvt. Ari provides patients with the opportunity to be a part of the solution when it comes to improving patient outcomes by filling out a simple, free survey. Young syndrome is a condition characterized by male infertility, damaged airways in the lungs bronchiectasis, and inflammation of the sinuses.
Hughes syndrome foundation nord national organization for. They first described the findings of the syndrome deep venous thrombosis and segmental pulmonary artery aneurysms in a total of four male patients with pulmonary artery aneurysms in 1959 1. Hughesstovin syndrome is a lifethreatening disorder of unknown etiology. If so, than you might be suffering from hughes syndrome, an immune system disorder that can threaten the health of both you and your baby. The aetiology of hughesstovin syndrome is still unknown and the natural course of the illness is usually fatal. Living with hughes syndrome by triona holden, 9780859698849, available at book depository with free delivery worldwide.
Williams syndrome genetic and rare diseases information. It is characterized by the association of multiple pulmonary artery aneurysms paas and peripheral venous thrombosis. The outcome of a blood clot depends on its size and location. They combine current evidence from clinical trials and the opinion of a. Mergers and acquisitions can be fearprovoking for employees and generate anxiety and stress.
The panel data ordinary least squares approach is the. Bring patients to the table during hospital merger. An accurate diagnosis of antiphospholipid syndrome aps is important because blood clots can have serious consequences. Two of these patients were their own while the remaining two had. Hughesstovin syndrome hss is a very rare clinical disorder characterized by thrombophlebitis and multiple pulmonary andor bronchial aneurysms. Phospholipids are fatty substances that are a normal part of all of your bodys cells. Antiphospholipid syndrome, or antiphospholipid antibody syndrome aps or apls, is an autoimmune, hypercoagulable state caused by antiphospholipid antibodies. These antibodies make the immune system work too hard. Hughesstovin syndrome hss, orpha228116 was named after two british physicians, drs. Pulmonary medium vessel vasculitis in an 11 year old boy.
The hughes syndrome foundations hsf mission is to provide information and education on hughes syndrome and support research for it. Hughesstovin syndrome hss is a very rare clinical disorder. Nonprogressive cerebellar ataxia and previous undetermined. In pregnancy, it is a leading cause of miscarriage, stillbirth and preeclampsia. The exact etiology and pathogenesis of hss is unknown. If aps is suspected, youll usually be referred to hospital to see either. University of groningen the impact of juvenile idiopathic.
The hughes stovin syndrome consists of deep venous thrombosis often involving the caval vein accompanied by single or multiple pulmonary arterial aneurysms. Blood clots can form in, or travel to, the arteries or veins in the brain, heart, kidneys, lungs, and limbs. Apr, 2011 hughes stovin syndrome hss is a very rare clinical disorder characterized by thrombophlebitis and multiple pulmonary andor bronchial aneurysms. It is named after the two british physicians, john patterson hughes and peter george ingle stovin, who first described it in 1959. The signs and symptoms of antiphospholipid antibody syndrome aps are related to abnormal blood clotting. Massive pulmonary hemorrhage caused by rupture of an aneurysm is a frequent terminal event. Management of thrombosis in antiphospholipid syndrome anticoagulation. The physician also decided to combine pulse therapy with methylprednisolone and. Pdf hughesstovin syndrome is a rare disorder of unknown etiology characterized by the association of. Here you can read posts from all over the web from people who wrote about antiphospholipid syndrome and rash, and check the relations between antiphospholipid syndrome and rash. Severe cardiovascular involvement in hughesstovin syndrome. They usually help defend the body against infections.